Miller was born on July 24, 1978, in Boston and grew up in New York City and Philadelphia. After graduating from Brown University with a bachelor's and master's in Classics (2000 and 2001, respectively), Miller then went on to teach Latin, Greek, and Shakespeare to high school students. She also studied for a year at the University of Chicago's Committee on Social Thought toward a Ph.D. and from 2009 to 2010 at the Yale School of Drama for an MFA in Dramaturgy and Dramatic Criticism. As of May 2012, Miller lived in Cambridge, Massachusetts teaching and writing.
Miller told a reporter from The Guardian that she has been inspired by a lot of books, poetry, and authors, including David Mitchell, Lorrie Moore, Anne Carson, and Virgil.
The Song of Achilles
Main article: The Song of Achilles
The Song of Achilles, Miller's debut novel, was released in September 2011. The book took her ten years to write. Set in Greece, the novel tells the story of a love affair between Achilles and Patroclus. The novel won the 17th annual Orange Prize for Fiction.
Circe, Miller's second novel, was released on April 10, 2018. The book is a modern reimagining told from the perspective of Circe, an enchantress in Greek mythology who is featured in Homer's Odyssey. Circe was ranked the second-greatest book of the 2010s by Paste. Tutor House ranked Circe in its top books for Classics students in 2021. An 8-part miniseries adaptation of the book has been greenlit for HBO Max. Rick Jaffa and Amanda Silver are set to write and produce the adaptation.